β-Lactones are prominent structural motifs found in various natural products and pharmaceutically significant compounds, exhibiting high biological activity and therapeutic potential. Due to their unique structural features, they serve as valuable intermediates in organic synthesis and play a crucial role in pharmaceutical research, including drug development. In this study, we present a novel protocol for the selective synthesis of β-lactones using N-protected alanine derivatives. This reaction employs palladium as a catalyst, with aryl iodides serving as the oxidant, leading to the selective formation of β-lactones.