2025 Spring International Convention of
The Pharmaceutical Society of Korea

2025 Spring
International Convention of PSK

04.21(MON) - 04.22(TUE)
D+77

Abstracts

P6-8

Annulative functionalization approach to poly-functionalized imidazo[1,2-a]pyridines

  • Ikyon Kim*1, Dageum Kang1, Myungho Jung1, Sunhee Lee1, Dohui Ku1
  • 1College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea

The reaction of enaminone with propargylamine allowed for a highly efficient domino process involving conjugate substitution, nucleophilic addition of the nitrogen to the pendant nitrile, and cycloisomerization, leading to a densely functionalized imidazo[1,2-a]pyridine via successive double ring closure.


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TODAY 2025. 07. 08

2025 Spring Convention

D+77

Conference infomation

Conference Schedule
Apr. 21(Mon) ~ 22(Tue), 2025
Conference Venue
Daegu Exhibition & Convention Center (EXCO) 10 Exco-ro, Buk-gu, Daegu, Republic of Korea
Location
Early Registration Period
Feb. 24(Mon) ~ Apr. 14(Mon), 2025
Abstract Submission Period
Feb. 24(Mon) ~ Apr. 3(Thu), 2025
Certificate of Attendance