2024 Spring International Convention of
The Pharmaceutical Society of Korea

2024 Spring
International Convention of PSK

04.17(WED) - 04.19(FRI)
D+28

Abstracts

P6-2

Preparation of sulfonamides under visible light Irradiation via a one-pot tricomponent reaction of arylazo sulfones, DABSO, and amines

  • Truong Giang Luu1, Hee-Kwon Kim*1
  • 1Department of Nuclear Medicine, Jeonbuk National University Medical School, Korea

Sulfonamide, a pivotal molecular motif within the realm of organic chemistry, has garnered considerable attention within the scientific community. Over the years, several studies have been conducted to develop straightforward, efficient, and cost-effective methods for synthesizing sulfonamides. Noteworthy, photochemical reactions have emerged as influential tools in organic synthesis and pharmaceutical research, attributable to their environmentally benign attributes, gentle reaction conditions, and facile controllability. Herein, we present a visible-light-induced one-pot tricomponent reaction to generate aryl sulfonamides. The method involved utilizing aryldiazo sulfone, DABSO, and amines as substrates, in the presence of CuBr2 as a coupling catalyst. With this strategy, various sulfonamides including pharmaceutical compounds were successfully yielded with high efficiency.


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TODAY 2024. 05. 17

2024 Spring Convention

D+28

Conference infomation

Conference Schedule
Apr. 17(Wed) ~ 19(Fri), 2024
Conference Venue
BPEX (Busan Port International Exhibition & Convention Center) Busan Metropolitan City, Republic of Korea
Location
Early Registration Period
Feb. 20(Tue) ~ Apr. 3(Wed), 2024
Abstract Submission Period
Feb. 20(Tue) ~ Apr. 3(Wed), 2024
Certificate of Attendance